Searchable abstracts of presentations at key conferences in endocrinology

ea0032p85 | Bone and Osteoporosis | ECE2013

HLA class I, Cw*01 and Cw*15 alleles can play a preventing role in serum IL17 elevation associated with postmenopausal osteoporosis in Hungary

Bohaty Ilona , Jurasne-Lukovics Monika , Somogyine-Vari Eva , Kozma Laszlo , Danko Katalin , Molnar Ildiko

IL17 proinflammatory cytokine through T cell activation has prominent bone-wasting effect. Our previous results highlighted the role of IL17 in postmenopausal osteoporosis. To demonstrate the HLA allele association with the increased IL17 levels in postmenopausal osteoporosis was the object of the study.HLA class I and II alleles were measured in 64 postmenopausal women (in four subgroups: with low IL17 (1, 3) and high (>3.04 pmol/l) IL17 levels (2, ...